Something I did, even thought it might sound weird, is I added limp stats to my HUD. I play 2NL 6 max and was seeing a ton of limping for a long time and had the same feelings that you did. I have Limp, Limp-Call, Limp-Fold, Limp-Raise on its own line. With these stat you can see how often they limp and of those times are what are the percentages of times that they call fold or raise to your iso.

I am no where near the level to be giving advice but my logical thought process would be that if you look at those stats and you have more of them prone to folding then iso raise. If more of them are prone to calling then maybe just limp behind. If you have a guys that goes crazy and limp raise everything than maybe folding these hands isn't the end of the world. If this is in the micros then I don't really think folding in marginal spots is that big of a deal. Eventually someone at your table is going to make a huge mistake that you can profit from, so why put yourself in all of these marginal spots where you could be the one who ends up making the mistake. I just try and avoid them and try and keep myself from getting frustrated and angry about the dumb crap that happens so that I can be there when they do make that mistake.

As it has been mentioned numerous times, limping is rather weak. I think that if you have these guys limp calling ATC then it is highly probable that at times you could get paid off when you smash the flop. I have seen limpers go at each other and end up stacking off, so you never know you might flop a flush or straight or a draw to them that hit, or a 2 pair that you can get paid off on. Remember these guys don't exactly think about what you have, let alone a range of things you could have. In most cases they are only concerned with the 2 cards they have. If they catch a piece of the flop you can usually get some value out of them. You just have to tread cautiously as they literally could have anything

I personally don't know what is MaxEV as I have never done analysis on it bt I am sure there is away with HEM2 or PT4 that you can look at theses spots or at the situation as a whole to determine which is best in the given situations.

If this isn't micros or you don't have a HUD then I guess nothing I said really helps! LOL!

Something makes me think that raising is the most +EV, but I also think that it increases the variance. Another option would be raising something like 3x-4x and hope that everybody calls. That way you sweeten the pot without investing too much, and when you hit it is easier to get your stack in because the pot is bigger. It is super exploitable, because if your opponents pay any attention they will find out fast what your smaller raises mean. But, it is possible that they are not paying attention at all and you can make this play. I do not know because I have never actually tried it.

There's no question if you have position and some one limps . RAISE. Iso the re tard.If he his bad enough to limp a premium,he will tell you the minute you iso. As he can't contain himself and will raise.
Printing money anytime anyone limps pre,I assure you.It doesn't matter what cards you have.

I am not talking about one limper. I am talking about bunch of limpers. In these situations it is likely that you get more than one caller and therefore you are not isolating the single limper.

One or three it's irrelevant, your printing money.

I'd call the weaker hands like 64s as these play very well multi-way and make weak pairs HU, plus I don't want to make a massive pot with weak draws. Then I'd raise your stronger hands like J9s. Against one limper I would raise hands like 64s as we're printing money with our CB.